Molecular Formula | C29H36O15 |
Molar Mass | 624.59 |
Density | 1.3090 (rough estimate) |
Melting Point | >124°C (Subl.) |
Boling Point | 583.81°C (rough estimate) |
Flash Point | 145.408°C |
Solubility | Very slightly dissolved in ethanol and acetone, insoluble in ether |
Vapor Presure | 0mmHg at 25°C |
Appearance | Powder |
Color | Yellow |
Storage Condition | Refrigerator |
Refractive Index | 1.5940 (estimate) |
MDL | MFCD01741310 |
Physical and Chemical Properties | White needle crystal water-soluble, soluble in methanol, ethanol, DMSO and other organic solvents, from fructus aurantii, citrus. |
Use | Used to increase the resistance of capillaries and normalize the permeability of capillaries |
HS Code | 29389090 |
Reference Show more | 1. [IF=2.391] Tan Si et al."Effects of three drying methods on polyphenol composition and antioxidant activities of Litchi chinensis Sonn.."Food Sci Biotechnol. 2020 Mar;29(3):351-358 2. [IF=4.24] Bo Zou et al."Structural identification and antioxidant potency evaluation of pomelo vinegar polyphenols."Food Biosci. 2022 Jun;47:101674 |
Plant source: | Fructus Aurantii Immaturus |
application | methyl hesperidin combined with VitC can prevent and treat hypertension and brain blood. in recent years, orange vitamin c granule has been developed. As early as the 1960s, it became the main raw material of "maitong" and became a vascular strengthening drug compatible with other drugs, which is widely used in clinical practice. |
physiological function | methyl hesperidin is a flavonoid compound formed by hesperidin through a toxic surface, which can increase the coronary flow of isolated rabbit heart, increase the cardiac output of dogs, reduce myocardial oxygen consumption, relax isolated rabbit aortic strips, reduce the vascular resistance of dog lower limbs, significantly reduce blood pressure and coronary, renal and cerebrovascular resistance, and increase coronary and renal blood flow. |
Synthesis method | Methyl hesperidin is derived from hesperidin (orange peel R) methylation. The traditional process is a liquid alkali method (sodium hydroxide method), hesperidin is dissolved in sodium hydroxide solution, and then methylation reagent-dimethyl sulfate is added for methylation reaction to obtain methyl hesperidin. The yield of this method is only 70.0%. |
use | used for content determination/identification/pharmacological experiments, etc. used to increase the resistance of capillaries and normalize capillary permeability |